BDBM13551 10-[2-(Diethylamino)-1-oxopropyl]-10H-phenothiazine::2-(diethylamino)-1-(10H-phenothiazin-10-yl)propan-1-one::AS-1397::CHEMBL1782730

SMILES CCN(CC)C(C)C(=O)N1c2ccccc2Sc2ccccc12

InChI Key InChIKey=QCEWCMMSOWEHFC-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 13551   

TargetCholinesterase(Horse)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM13551(2-(diethylamino)-1-(10H-phenothiazin-10-yl)propan-...)
Affinity DataIC50: 840nMAssay Description:Inhibition of Equine serum BChE using butyrylthiocholine iodide as a substrate after 20 mins by Ellman's assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM13551(2-(diethylamino)-1-(10H-phenothiazin-10-yl)propan-...)
Affinity DataIC50: 3.37E+3nMAssay Description:Inhibition of human erythrocytes BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetCholinesterase(Human)
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM13551(2-(diethylamino)-1-(10H-phenothiazin-10-yl)propan-...)
Affinity DataIC50: 3.37E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changed at 412 nm and was monitored with spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2007
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM13551(2-(diethylamino)-1-(10H-phenothiazin-10-yl)propan-...)
Affinity DataIC50: 3.37E+3nMAssay Description:Inhibition of human plasma BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Pacific electric ray)
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM13551(2-(diethylamino)-1-(10H-phenothiazin-10-yl)propan-...)
Affinity DataIC50: 3.47E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changed at 412 nm and was monitored with spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2007
Entry Details Article
PubMed