BDBM50052593 3-Ethynyl-5-((S)-1-methyl-azetidin-2-yl)-pyridine::3-Ethynyl-5-((S)-1-methyl-pyrrolidin-2-yl)-pyridine::Altinicline::CHEMBL111659::US10667515, Compound (S)-SIB 1508Y
SMILES CN1CCC[C@H]1c1cncc(c1)C#C
InChI Key InChIKey=NUPUDYKEEJNZRG-LBPRGKRZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50052593
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataEC50: 1.80E+3nMAssay Description:The compound was tested on recombinant human alpha2-beta4 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataEC50: 1.80E+3nMAssay Description:The compound was tested on recombinant human alpha-1-beta-1-gamma-delta cell lines of human embryonic kidney for nicotinic acetylcholine receptor ago...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataIC50: 8.90E+3nMAssay Description:The compound was tested on recombinant human alpha3-beta4 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-4(Homo sapiens (Human))
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataEC50: 5.00E+3nMAssay Description:The compound was tested on recombinant human alpha2-beta4 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-4(Homo sapiens (Human))
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataEC50: 5.00E+3nMAssay Description:The compound was tested on recombinant human alpha2-beta4 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Homo sapiens (Human))
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataEC50: 9.00E+3nMAssay Description:The compound was tested on recombinant human alpha4-beta4 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair
TargetResistance to inhibitors of cholinesterase protein 3(Pig roundworm)
Iowa State University Research Foundation
US Patent
Iowa State University Research Foundation
US Patent
Affinity DataEC50: 370nMAssay Description:Nematode eggs are isolated from fresh feces by centrifugation and flotation. The eggs are washed and inspected to confirm embryonation has not starte...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataEC50: 2.30E+4nMAssay Description:The compound was tested on recombinant human alpha3-beta4 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataEC50: 2.30E+4nMAssay Description:The compound was tested on recombinant human alpha3-beta4 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor; alpha2/beta4(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences
Curated by ChEMBL
The Danish University Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataEC50: 3.20E+3nMAssay Description:Effective concentration against Nicotinic acetylcholine receptor alpha2-beta4More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences
Curated by ChEMBL
The Danish University Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Effective concentration against Nicotinic acetylcholine receptor alpha 7More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences
Curated by ChEMBL
The Danish University Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataEC50: 3.20E+3nMAssay Description:Effective concentration against Nicotinic acetylcholine receptor alpha3-beta2More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataEC50: 320nMAssay Description:Effective concentration against Nicotinic acetylcholine receptor alpha4-beta2More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Homo sapiens (Human))
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataEC50: 9.00E+3nMAssay Description:The compound was tested on recombinant human alpha4-beta4 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair