BDBM50277171 Asclepin::CHEBI:2867

SMILES [H][C@@]1(CC[C@]2(O)[C@]3([H])CC[C@@]4([H])C[C@@]5([H])O[C@]6([H])O[C@H](C)C[C@H](OC(C)=O)[C@]6(O)O[C@]5([H])C[C@]4(C=O)[C@@]3([H])CC[C@]12C)C1=CC(=O)OC1

InChI Key InChIKey=OXKMZIABKYHLAR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50277171   

TargetNeurogenic locus notch homolog protein 1(Human)
Chiba University

Curated by ChEMBL
LigandPNGBDBM50277171(CHEBI:2867 | Asclepin)
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant mouse N-terminal FLAG-tagged Notch1 (1704 to 2531 residues) expressed in human LS174T cells assessed as reduction in doxycy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2020
Entry Details Article
PubMed