BDBM50473497 BAY-507952::CHEMBL157769

SMILES COC(=O)c1c(Br)c(OC)cc(O)c1CSC[C@H](Nc1nc(cs1)-c1ccc(cc1)[N+]([O-])=O)C1=NOCCO1

InChI Key InChIKey=MRGBDARDZKENAD-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50473497   

TargetDNA topoisomerase 2-beta(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50473497(BAY-507952 | CHEMBL157769)
Affinity DataIC50: 625nMAssay Description:Antibacterial activity against Micrococcus luteus DNA gyrase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-beta(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50473497(BAY-507952 | CHEMBL157769)
Affinity DataIC50: 781nMAssay Description:Antibacterial activity against Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50473497(BAY-507952 | CHEMBL157769)
Affinity DataIC50: 9.38E+4nMAssay Description:Antibacterial activity against human DNA Topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50473497(BAY-507952 | CHEMBL157769)
Affinity DataIC50: 1.87E+5nMAssay Description:Antibacterial activity against Escherichia coli DNA topoisomerase IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50473497(BAY-507952 | CHEMBL157769)
Affinity DataIC50: 3.75E+5nMAssay Description:Antibacterial activity against calf thymus Topo I.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50473497(BAY-507952 | CHEMBL157769)
Affinity DataIC50: 3.75E+5nMAssay Description:Antibacterial activity against human DNA Topo I.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed