BDBM100227 (8R)-3-[3-[2-(4-chloranylphenoxy)ethanoylamino]phenyl]-7-[2-(4-nitrophenyl)ethanoyl]-1-oxa-2,7-diazaspiro[4.4]non-2-ene-8-carboxamide::(8R)-3-[3-[[2-(4-chlorophenoxy)-1-oxoethyl]amino]phenyl]-7-[2-(4-nitrophenyl)-1-oxoethyl]-1-oxa-2,7-diazaspiro[4.4]non-2-ene-8-carboxamide::(8R)-3-[3-[[2-(4-chlorophenoxy)acetyl]amino]phenyl]-7-[2-(4-nitrophenyl)acetyl]-1-oxa-2,7-diazaspiro[4.4]non-2-ene-8-carboxamide::MLS000562030::SMR000390714::cid_16682003

SMILES CNCc1cc(-c2ccc(OC(C)c3c(F)cccc3F)cc2F)n(S(=O)(=O)c2cccnc2)c1

InChI Key InChIKey=ZCKWVSYCWHMJGF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 100227   

LigandChemical structure of BindingDB Monomer ID 100227BDBM100227(US20260001864, Compound 67)
Affinity DataIC50: 41nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent