BDBM101815 US9695160, 36::US9796707, Compound 36

SMILES COc1cc(ccn1)-c1ccc(o1)C(=O)Nc1cc(ccc1N1CCN(Cc2ccccn2)CC1)C(F)(F)F

InChI Key InChIKey=CRVLSPVCOJDAJT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 101815   

TargetSRSF protein kinase 1(Human)
The University of Nottingham

US Patent
LigandPNGBDBM101815(US9695160, 36 | US9796707, Compound 36)
Affinity DataIC50: 170nMAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
The University of Nottingham

US Patent
LigandPNGBDBM101815(US9695160, 36 | US9796707, Compound 36)
Affinity DataIC50: 170nMT: 2°CAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent