BDBM10388 methyl 3-{12-bromo-7-methyl-3,5-dioxo-4,8-diazatricyclo[7.4.0.0^{2,6}]trideca-1(13),2(6),7,9,11-pentaen-4-yl}propanoate::pyrrolo[3,4-c]quinoline 6n

SMILES COC(=O)CCN1C(=O)c2c(C1=O)c1cc(Br)ccc1nc2C

InChI Key InChIKey=BDXDCSVSLUUFJF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10388   

TargetCaspase-3(Human)
Chemical Diversity Research Institute

LigandPNGBDBM10388(methyl 3-{12-bromo-7-methyl-3,5-dioxo-4,8-diazatri...)
Affinity DataIC50: 1.08E+3nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2006
Entry Details Article
PubMed