BDBM10401 methyl (2S)-2-{[7-methyl-3,5-dioxo-4-(1,3,5-trimethyl-1H-pyrazol-4-yl)-4,8-diazatricyclo[7.4.0.0^{2,6}]trideca-1(13),2(6),7,9,11-pentaene-12-]sulfonamido}-3-phenylpropanoate::pyrrolo[3,4-c]quinoline 8d

SMILES COC(=O)[C@H](Cc1ccccc1)NS(=O)(=O)c1ccc2nc(C)c3C(=O)N(C(=O)c3c2c1)c1c(C)nn(C)c1C

InChI Key InChIKey=GKYSJQPOFCDKBA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10401   

TargetCaspase-3(Human)
Chemical Diversity Research Institute

LigandPNGBDBM10401(methyl (2S)-2-{[7-methyl-3,5-dioxo-4-(1,3,5-trimet...)
Affinity DataIC50: 23nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2006
Entry Details Article
PubMed