BDBM104728 US8569308, 148::US8569308, 222

SMILES Cc1cccc(c1)C(=O)Nc1cncc(Oc2cncnc2)n1

InChI Key InChIKey=BUBJHGRJCKENAV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 104728   

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 104728BDBM104728(US8569308, 222 | US8569308, 148)
Affinity DataIC50: 212nMAssay Description:Negative allosteric modulator activity at rat mGlu5 expressed in HEK293A cells assessed as reduction in glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 104728BDBM104728(US8569308, 222 | US8569308, 148)
Affinity DataIC50: 214nMAssay Description:Negative allosteric modulator activity at rat mGlu5 expressed in HEK293A cells assessed as reduction in glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed