BDBM105239 US8580782, 7

SMILES Clc1ccccc1-c1cc(NCc2ccncc2)n2ncc(Br)c2n1

InChI Key InChIKey=WVUDZDGNXHQQNC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 105239   

TargetCyclin-dependent kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM105239(US8580782, 7)
Affinity DataIC50: 6nMpH: 8.0Assay Description:CDK2 kinase assays (either cyclin A or cyclin E-dependent) were performed in low protein binding 96-well plates (Corning Inc., Corning, N.Y.).More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
US Patent

TargetCyclin-dependent kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM105239(US8580782, 7)
Affinity DataIC50: 10nMpH: 8.0Assay Description:CDK2 kinase assays (either cyclin A or cyclin E-dependent) were performed in low protein binding 96-well plates (Corning Inc., Corning, N.Y.).More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
US Patent