BDBM1060 2-{[(6-ethyl-5-methyl-2-oxo-1,2-dihydropyridin-3-yl)amino]methyl}-2,3-dihydro-1H-isoindole-1,3-dione::L-619,757

SMILES CCc1[nH]c(=O)c(NCN2C(=O)c3ccccc3C2=O)cc1C

InChI Key InChIKey=QOUSSLJUEXJDBB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 1060   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM1060(2-{[(6-ethyl-5-methyl-2-oxo-1,2-dihydropyridin-3-y...)
Affinity DataIC50: 887nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2004
Entry Details Article
PubMed