BDBM10693 3-{[methyl({7-[(9-oxo-9H-xanthen-3-yl)oxy]heptyl})amino]methyl}phenyl N-methylcarbamate::CHEMBL189957::Xanthostigmine deriv. 2::aminoalkoxyaryl deriv. 12b

SMILES CNC(=O)Oc1cccc(CN(C)CCCCCCCOc2ccc3c(c2)oc2ccccc2c3=O)c1

InChI Key InChIKey=QKVHGMOFMMASRA-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 10693   

TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM10693(CHEMBL189957 | 3-{[methyl({7-[(9-oxo-9H-xanthen-3-...)
Affinity DataIC50: 0.320nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM10693(CHEMBL189957 | 3-{[methyl({7-[(9-oxo-9H-xanthen-3-...)
Affinity DataIC50: 0.320nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM10693(CHEMBL189957 | 3-{[methyl({7-[(9-oxo-9H-xanthen-3-...)
Affinity DataIC50: 0.320nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM10693(CHEMBL189957 | 3-{[methyl({7-[(9-oxo-9H-xanthen-3-...)
Affinity DataIC50: 0.320nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM10693(CHEMBL189957 | 3-{[methyl({7-[(9-oxo-9H-xanthen-3-...)
Affinity DataIC50: 0.320nMAssay Description:Inhibition of human erythrocyte AchEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM10693(CHEMBL189957 | 3-{[methyl({7-[(9-oxo-9H-xanthen-3-...)
Affinity DataIC50: 0.320nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM10693(CHEMBL189957 | 3-{[methyl({7-[(9-oxo-9H-xanthen-3-...)
Affinity DataIC50: 16.5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM10693(CHEMBL189957 | 3-{[methyl({7-[(9-oxo-9H-xanthen-3-...)
Affinity DataIC50: 16.5nMAssay Description:Inhibition of human serum BuChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM10693(CHEMBL189957 | 3-{[methyl({7-[(9-oxo-9H-xanthen-3-...)
Affinity DataIC50: 16.5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM10693(CHEMBL189957 | 3-{[methyl({7-[(9-oxo-9H-xanthen-3-...)
Affinity DataIC50: 52nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 30 mins followed by substrate addition measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed