BDBM106972 US8592457, 7-7

SMILES COc1nc(CNC(=O)c2cc(ncc2-c2nccs2)-c2cncc(C)c2)ccc1C1CC1

InChI Key InChIKey=IVIBTAHBQDWLMQ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 106972   

TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM106972(US8592457, 7-7)
Affinity DataKi:  0.970nM ΔG°:  -12.8kcal/molepH: 7.4 T: 2°CAssay Description:Assay methodology using FLIPR Ca2+ Flux Assay (Okumura et al., Biochem. Biophys. Res. Comm. 280:976-981, 2001).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent