BDBM107274 US8598345, 210::US8598345, Table 1-60/2-14

SMILES Cc1nc(NC(=O)c2cc(Oc3cncnc3)ccn2)sc1F

InChI Key InChIKey=UQCVDDWVSFSTNQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 107274   

TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University

US Patent
LigandPNGBDBM107274(US8598345, 210 | US8598345, Table 1-60/2-14)
Affinity DataIC50: 943nMAssay Description:mGluR5 activity was determined in a cell-based assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM107274(US8598345, 210 | US8598345, Table 1-60/2-14)
Affinity DataIC50: 981nMAssay Description:mGluR5 activity was determined in a cell-based assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent