BDBM107655 US8575157, 29

SMILES C[C@H](N1CC[C@@](CCCO)(OC1=O)c1ccccc1)c1ccc(cc1)-c1ccc(=O)[nH]c1

InChI Key InChIKey=WJULDYZURIKYHG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 107655   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM107655(US8575157, 29)
Affinity DataIC50: 1.39nMAssay Description:The inhibition of a microsomal preparation of 11β-HSD1 by compounds of the invention was measured essentially as previously described (K. Solly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM107655(US8575157, 29)
Affinity DataIC50: 2.76nMAssay Description:Inhibition assay using 11β-HSD1 in the presence of 50% human plasma. More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

TargetCytochrome P450 2C9(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM107655(US8575157, 29)
Affinity DataIC50: 7.50E+3nMAssay Description:The inhibition of recombinant CYP2C9 by compounds of the invention was measured using a commercial kit from Invitrogen (cat #2859).More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent