BDBM10784 1-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-4-yl N-ethyl-N-methylcarbamate::Aminoindan deriv. 23b::N-propargylaminoindan 23b

SMILES CCN(C)C(=O)Oc1cccc2C(CCc12)NCC#C

InChI Key InChIKey=CAFPZIPDWWVNRP-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 10784   

TargetCarboxylic ester hydrolase(Horse)
Teva Pharmaceutical Industries

LigandPNGBDBM10784(1-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-4-yl ...)
Affinity DataIC50: 19nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM10784(1-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-4-yl ...)
Affinity DataIC50: 19nMAssay Description:Inhibition of MAO-A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Teva Pharmaceutical Industries

LigandPNGBDBM10784(1-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-4-yl ...)
Affinity DataIC50: 830nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM10784(1-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-4-yl ...)
Affinity DataIC50: 830nMAssay Description:Inhibition of MAO-B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Teva Pharmaceutical Industries

LigandPNGBDBM10784(1-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-4-yl ...)
Affinity DataIC50: 2.15E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM10784(1-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-4-yl ...)
Affinity DataIC50: 2.15E+3nMAssay Description:Inhibition of human BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Teva Pharmaceutical Industries

LigandPNGBDBM10784(1-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-4-yl ...)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of recombinant human AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Teva Pharmaceutical Industries

LigandPNGBDBM10784(1-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-4-yl ...)
Affinity DataIC50: 1.50E+5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed