BDBM108025 US8604218, 2.039

SMILES OCCOc1cccc(CN2CC[C@H](C2)Nc2cccc3cnccc23)c1

InChI Key InChIKey=HRCKLYFDWWYCLS-LJQANCHMSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 108025   

TargetRho-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM108025(US8604218, 2.039)
Affinity DataKi:  5nMAssay Description:Inhibition of ROCK1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM108025(US8604218, 2.039)
Affinity DataKi:  14nMAssay Description:Inhibition of ROCK2 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM108025(US8604218, 2.039)
Affinity DataIC50:  101nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent