BDBM108053 4-((4-((2,3-dimethyl-2H-indazole-6-yl)(methyl) amino)pyrimidin-2-yl)amino)-N-(4-methylpyrimidin- 2-yl)benzenesulfonamide (P2d)

SMILES CN(c1ccc2c(C)n(C)nc2c1)c1ccnc(Nc2ccc(cc2)S(=O)(=O)Nc2nccc(C)n2)n1

InChI Key InChIKey=ZMSRESYSODUSBK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 108053   

TargetVascular endothelial growth factor receptor 2(Human)
Shandong Institute of Pharmaceutical Industry

LigandPNGBDBM108053(4-((4-((2,3-dimethyl-2H-indazole-6-yl)(methyl) ami...)
Affinity DataIC50: 25nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Shandong Institute of Pharmaceutical Industry

LigandPNGBDBM108053(4-((4-((2,3-dimethyl-2H-indazole-6-yl)(methyl) ami...)
Affinity DataIC50: 62nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2014
Entry Details Article
PubMed