BDBM108054 4-((4-((2,3-dimethyl-2H-indazole-6-yl)amino) pyrimidin-2-yl)amino)-N-(4,6-dimethylpyrimidin-2- yl)benzenesulfonamide (P1e)

SMILES Cc1n(C)nc2cc(Nc3ccnc(Nc4ccc(cc4)S(=O)(=O)Nc4nc(C)cc(C)n4)n3)ccc12

InChI Key InChIKey=NVPYFEWIGMLJPC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 108054   

TargetVascular endothelial growth factor receptor 2(Human)
Shandong Institute of Pharmaceutical Industry

LigandPNGBDBM108054(4-((4-((2,3-dimethyl-2H-indazole-6-yl)amino) pyrim...)
Affinity DataIC50: 120nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Shandong Institute of Pharmaceutical Industry

LigandPNGBDBM108054(4-((4-((2,3-dimethyl-2H-indazole-6-yl)amino) pyrim...)
Affinity DataIC50: 360nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2014
Entry Details Article
PubMed