BDBM108057 4-((4-((2,3-dimethyl-2H-indazole-6-yl)(methyl) amino)pyrimidin-2-yl)amino)-N-(5-methylisoxazol- 3-yl)benzenesulfonamide (P2f)

SMILES CN(c1ccc2c(C)n(C)nc2c1)c1ccnc(Nc2ccc(cc2)S(=O)(=O)Nc2cc(C)on2)n1

InChI Key InChIKey=SCSKGPNMMVUABW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 108057   

TargetTyrosine-protein kinase ABL1(Human)
Shandong Institute of Pharmaceutical Industry

LigandPNGBDBM108057(4-((4-((2,3-dimethyl-2H-indazole-6-yl)(methyl) ami...)
Affinity DataIC50: 320nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2014
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shandong Institute of Pharmaceutical Industry

LigandPNGBDBM108057(4-((4-((2,3-dimethyl-2H-indazole-6-yl)(methyl) ami...)
Affinity DataIC50: 650nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2014
Entry Details Article
PubMed