BDBM108091 US8598163, 1

SMILES C[C@H](N1CC[C@@](CC(C)(C)O)(OC1=O)c1ccccc1)c1ccc(cc1)-c1ccc2nccn2n1

InChI Key InChIKey=MSTDOBPWYBQASR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 108091   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM108091(US8598163, 1)
Affinity DataIC50: 1nMpH: 7.4Assay Description:The inhibition of a microsomal preparation of 11β-HSD1 by compounds of the invention was measured essentially as previously described (K. Solly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM108091(US8598163, 1)
Affinity DataIC50: 2.90nMpH: 7.4Assay Description:The inhibition of a microsomal preparation of 11β-HSD1 by compounds of the invention was measured essentially as previously described (K. Solly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
US Patent