BDBM108093 US8598163, 5

SMILES CC(C)[C@@]1(CC(C)(C)O)CCN([C@@H](C)c2ccc(cc2)-c2ccc3nc(C)nn3c2)C(=O)O1

InChI Key InChIKey=DERAIVBXARVNNP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 108093   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM108093(US8598163, 5)
Affinity DataIC50: 22nMpH: 7.4Assay Description:The inhibition of a microsomal preparation of 11β-HSD1 by compounds of the invention was measured essentially as previously described (K. Solly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM108093(US8598163, 5)
Affinity DataIC50: 1.00E+3nMpH: 7.4Assay Description:The inhibition of a microsomal preparation of 11β-HSD1 by compounds of the invention was measured essentially as previously described (K. Solly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
US Patent