BDBM108094 US8598163, 6

SMILES CC(C)(O)C[C@@]1(CCN([C@H]2CCCN(C2)c2ccc3ncnn3c2)C(=O)O1)c1ccccc1

InChI Key InChIKey=NCIBJRVCGDORHH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 108094   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM108094(US8598163, 6)
Affinity DataIC50: 40nMpH: 7.4Assay Description:The inhibition of a microsomal preparation of 11β-HSD1 by compounds of the invention was measured essentially as previously described (K. Solly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
US Patent