BDBM11042 N-(2-fluoro-4-sulfamoylphenyl)-3-({2-[(2-fluoro-4-sulfamoylphenyl)carbamoyl]ethyl}disulfanyl)propanamide::N-[4-(aminosulfonyl)-2-fluorophenyl]-3-[(3-{[4-(aminosulfonyl)-2-fluorophenyl]amino}-3-oxopropyl)dithio]propanamide::disulfide-containing sulfonamide 2b

SMILES NS(=O)(=O)c1ccc(NC(=O)CCSSCCC(=O)Nc2ccc(cc2F)S(N)(=O)=O)c(F)c1

InChI Key InChIKey=JPGZMPRBPBLABU-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 11042   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11042(N-(2-fluoro-4-sulfamoylphenyl)-3-({2-[(2-fluoro-4-...)
Affinity DataKi:  64nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11042(N-(2-fluoro-4-sulfamoylphenyl)-3-({2-[(2-fluoro-4-...)
Affinity DataKi:  69nM ΔG°:  -9.66kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11042(N-(2-fluoro-4-sulfamoylphenyl)-3-({2-[(2-fluoro-4-...)
Affinity DataKi:  79nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed