BDBM110536 US8614234, 4::US9725433, 4

SMILES COC(=O)CNC(=O)c1c[nH]c(-c2cc(Oc3cccc(NC(=O)c4occc4C)c3)ccn2)c1

InChI Key InChIKey=VYVRNJVJSGNVQN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 110536   

TargetVascular endothelial growth factor receptor 2(Human)
Allergan

US Patent
LigandChemical structure of BindingDB Monomer ID 110536BDBM110536(US8614234, 4 | US9725433, 4)
Affinity DataIC50: 29nMAssay Description:Automated FLIPR (Fluorometric Imaging Plate Reader) technology was used to screen for inhibitors of VEGF induced increases in intracellular calcium l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Allergan

US Patent
LigandChemical structure of BindingDB Monomer ID 110536BDBM110536(US8614234, 4 | US9725433, 4)
Affinity DataIC50: 29nMpH: 7.2 T: 2°CAssay Description:Kinase assays were performed in 96 well microtiter plates that were coated overnight with 30.mu.g of poly-Glu-Tyr (4:1) in 10 mM Phosphate Buffered S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent