BDBM110695 US8614206, 115

SMILES Cn1ncc(NC(=O)c2nc(sc2N)-c2c(F)ccc(C3CC3)c2F)c1N1CCC[C@@H](N)CC1

InChI Key InChIKey=ZJUBIRAOAVCHJR-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 110695   

TargetSerine/threonine-protein kinase pim-1(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM110695(US8614206, 115)
Affinity DataKi:  0.0150nMpH: 7.2Assay Description:PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent