BDBM110696 US8614206, 116

SMILES Cc1ccc(F)c(-c2nc(C(=O)Nc3cnn(C)c3N3CCC[C@@H](N)CC3)c(N)s2)c1F

InChI Key InChIKey=IPKJAXOUJBYVRS-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 110696   

TargetSerine/threonine-protein kinase pim-1(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM110696(US8614206, 116)
Affinity DataKi:  0.0100nMpH: 7.2Assay Description:PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent