BDBM110751 US8614206, 284

SMILES Cc1ccc(F)c(c1)-c1nc(C(=O)Nc2cnn(C)c2N2CC[C@H](N)CC(F)(F)C2)c(N)s1

InChI Key InChIKey=ONQRCCQTRXWVFT-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 110751   

TargetSerine/threonine-protein kinase pim-1(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM110751(US8614206, 284)
Affinity DataKi:  0.0150nMpH: 7.2Assay Description:PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent