BDBM111346 US8614253, 29-6::US8614253, 42-4::US9241942, 42-4

SMILES CN(C)C(=O)c1ccc(cc1)-c1ccc2c(C=O)c(O)ccc2c1

InChI Key InChIKey=SXLLZNJNUOZIPJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 111346   

LigandChemical structure of BindingDB Monomer ID 111346BDBM111346(US8614253, 42-4 | US8614253, 29-6 | US9241942, 42-...)
Affinity DataIC50: 36nMpH: 7.5 T: 2°CAssay Description:IRE-1 alpha, T1 RNase, and RNase A assays carried out in vitro with several o-vanillin derivatives to demonstrate selectivity of the derivatives for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 111346BDBM111346(US8614253, 42-4 | US8614253, 29-6 | US9241942, 42-...)
Affinity DataIC50: 36nMpH: 7.5 T: 2°CAssay Description:IRE-1 alpha, T1 RNase, and RNase A assays carried out in vitro with several o-vanillin derivatives to demonstrate selectivity of the derivatives for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 111346BDBM111346(US8614253, 42-4 | US8614253, 29-6 | US9241942, 42-...)
Affinity DataIC50: 36nMpH: 7.5Assay Description:A fusion protein comprising glutathione S transferase (GST) and human IRE-1α (GST-IRE-1α) was obtained from a 500 ml baculovirus-infected i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 111346BDBM111346(US8614253, 42-4 | US8614253, 29-6 | US9241942, 42-...)
Affinity DataIC50: 36nMpH: 7.5Assay Description:A fusion protein comprising glutathione S transferase (GST) and human IRE-1α (GST-IRE-1α) was obtained from a 500 ml baculovirus-infected i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent