BDBM112489 US8623885, 30

SMILES C[C@H]1CC[C@@H](CC1)n1c2cnccc2c2cnc(Nc3ccc4CCN(Cc4n3)C(=O)CO)nc12

InChI Key InChIKey=GWYAHYQRVHZFDB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 112489   

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandPNGBDBM112489(US8623885, 30)
Affinity DataIC50: 6.30nMpH: 7.4Assay Description:The CDK4 and CDK1 inhibitory activity of the CDK4/6-FLT3 inhibitors was determined with a filtration kinase assay. The compounds, kinase and substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent