BDBM112695 US8629158, 20::US8629158, 21::US8629158, 8

SMILES O=c1cc(OCc2ccccc2)ccn1-c1ccc2c3C4CCC(Cc3[nH]c2c1)N4

InChI Key InChIKey=DOUMNJOBZGMSMH-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 112695   

TargetMelanin-concentrating hormone receptor 1(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM112695(US8629158, 20 | US8629158, 21 | US8629158, 8)
Affinity DataKi:  9.30nM ΔG°:  -10.9kcal/molepH: 7.4 T: 2°CAssay Description:Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetMelanin-concentrating hormone receptor 1(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM112695(US8629158, 20 | US8629158, 21 | US8629158, 8)
Affinity DataKi:  9.80nM ΔG°:  -10.9kcal/molepH: 7.4 T: 2°CAssay Description:Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetMelanin-concentrating hormone receptor 1(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM112695(US8629158, 20 | US8629158, 21 | US8629158, 8)
Affinity DataKi:  39nM ΔG°:  -10.1kcal/molepH: 7.4 T: 2°CAssay Description:Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent