BDBM112879 US9695181, IId

SMILES CN(CCCC(=O)NO)CCCn1nc(-c2ccc(NC(=O)Nc3cccc(C)c3)cc2)c2c(N)ncnc12

InChI Key InChIKey=QWIISSFUUDDVFV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 112879   

TargetHistone deacetylase 1(Human)
Double Rider Medicine

US Patent
LigandPNGBDBM112879(US9695181, IId)
Affinity DataIC50: 13.8nMT: 2°CAssay Description:Enzymatic activity was tested in 96-well or 384-well flat microwell plate by fluorescence detection and taking Ac-Lys-Tyr-Lys(Ac)-AMC as substrate. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Double Rider Medicine

US Patent
LigandPNGBDBM112879(US9695181, IId)
Affinity DataIC50: 99.9nMAssay Description:Inhibition of Compound IIa, IIb, IIc and IId on the Activity of Catalyzing Substrate Phosphorylation of KDR (VEGFR2) Protein Tyrosine Kinase at the M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Double Rider Medicine

US Patent
LigandPNGBDBM112879(US9695181, IId)
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of Compound IIa, IIb, IIc and IId on the Activity of Catalyzing Substrate Phosphorylation of KDR (VEGFR2) Protein Tyrosine Kinase at the M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent