BDBM113499 US8633204, 221

SMILES Cc1nc(N)nc2n(CC3CCOC3)c(=O)c(cc12)-c1cnc2[nH]ccc2c1

InChI Key InChIKey=OVFRALSDTFZPRQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 113499   

LigandPNGBDBM113499(US8633204, 221)
Affinity DataIC50: 2.80nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent