BDBM11396 1,1-dioxo-2-[2-(propylamino)ethyl]-2H-1,7,2-thieno[3,2-e][1,2]thiazine-6-sulfonamide hydrochloride::2-[2-(Propylamino)ethyl]-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide hydrochloride::2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide 4::Compound 5d

SMILES CCCNCCN1C=Cc2cc(sc2S1(=O)=O)S(N)(=O)=O

InChI Key InChIKey=LGHKMXPOEQXMNC-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 11396   

TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11396(1,1-dioxo-2-[2-(propylamino)ethyl]-2H-1,7,2-thieno...)
Affinity DataKi:  0.520nM ΔG°:  -13.2kcal/molepH: 7.4 T: 37°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Human)
Alcon Research

LigandPNGBDBM11396(1,1-dioxo-2-[2-(propylamino)ethyl]-2H-1,7,2-thieno...)
Affinity DataIC50:  73.6nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11396(1,1-dioxo-2-[2-(propylamino)ethyl]-2H-1,7,2-thieno...)
Affinity DataIC50:  2.25nMpH: 7.2 T: 4°CAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed