BDBM114599 1-[6-[1-methyl-5-(5-methyl-1H-indazol-4-yl)-4-(3-pyridyl)imidazol-2-yl]-2-azaspiro[3.3]heptan-2-yl]prop-2-en-1-one::US20260060961, Example 3

SMILES C=CC(=O)N1CC2(CC(c3nc(-c4cccnc4)c(-c4c(C)ccc5[nH]ncc45)n3C)C2)C1

InChI Key InChIKey=BRGDRORGNMTGAI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 114599   

TargetGTPase KRas [G12C](Human)
Jazz Pharmaceuticals Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 114599BDBM114599(1-[6-[1-methyl-5-(5-methyl-1H-indazol-4-yl)-4-(3-p...)
Affinity DataIC50: 1.00E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2011
Entry Details
US Patent