BDBM114616 N,N-dimethyl-2-[4-[1-methyl-5-(5-methyl-1H-indazol-4-yl)-2-(2-prop-2-enoyl-2-azaspiro[3.3]heptan-6-yl)imidazol-4-yl]phenoxy]acetamide::US20260060961, Example 19

SMILES C=CC(=O)N1CC2(CC(c3nc(-c4ccc(OCC(=O)N(C)C)cc4)c(-c4c(C)ccc5[nH]ncc45)n3C)C2)C1

InChI Key InChIKey=QGWBVCYWGZEUCS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 114616   

TargetGTPase KRas [G12C](Human)
Jazz Pharmaceuticals Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 114616BDBM114616(N,N-dimethyl-2-[4-[1-methyl-5-(5-methyl-1H-indazol...)
Affinity DataIC50: 5.50E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2011
Entry Details
US Patent