BDBM114746 1-(4-methyl-1,3-thiazol-2-yl)-3-(2-nitrophenyl)urea::1-(4-methyl-2-thiazolyl)-3-(2-nitrophenyl)urea::1-(4-methylthiazol-2-yl)-3-(2-nitrophenyl)urea::MLS000672095::N-(4-methyl-1,3-thiazol-2-yl)-N'-(2-nitrophenyl)urea::SMR000293525::cid_2950184

SMILES CC(c1ccc(C(F)(F)F)nc1)n1nc(C#N)c2c(=O)[nH]c(N(C)C(c3ncccn3)C3CCC3)nc21

InChI Key InChIKey=LQYSRVCLRUOTQB-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 114746   

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 114746BDBM114746(6-[[cyclo- butyl(pyrimidin- 2-yl)methyl]- methyl- ...)
Affinity DataKi:  8.96nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent