BDBM114778 2-(5-pyridin-2-ylthiophen-2-yl)pyridine::2-[5-(2-pyridinyl)-2-thiophenyl]pyridine::2-[5-(2-pyridyl)-2-thienyl]pyridine::MLS000851103::SMR000457346::cid_2801704

SMILES CC(c1ccc(C(F)(F)F)nc1)n1nc(C#N)c2c(=O)[nH]c(N3CCC3c3ccc(F)cc3)nc21

InChI Key InChIKey=NIJMGWPTVYSTCQ-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 114778   

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 114778BDBM114778(6-[2-(4- fluorophenyl) azetidin-1-yl]-4- oxo-1-[1-...)
Affinity DataKi:  1.05nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent