BDBM114810 (6Z)-6-[5-[2-(2-methylpiperidin-1-yl)-2-oxidanylidene-ethyl]sulfanyl-3H-1,3,4-oxadiazol-2-ylidene]cyclohexa-2,4-dien-1-one::(6Z)-6-[5-[2-(2-methylpiperidin-1-yl)-2-oxoethyl]sulfanyl-3H-1,3,4-oxadiazol-2-ylidene]cyclohexa-2,4-dien-1-one::(6Z)-6-[5-[[2-(2-methyl-1-piperidinyl)-2-oxoethyl]thio]-3H-1,3,4-oxadiazol-2-ylidene]-1-cyclohexa-2,4-dienone::(6Z)-6-[5-[[2-keto-2-(2-methylpiperidino)ethyl]thio]-3H-1,3,4-oxadiazol-2-ylidene]cyclohexa-2,4-dien-1-one::2-[5-(2-Hydroxy-phenyl)-[1,3,4]oxadiazol-2-ylsulfanyl]-1-(2-methyl-piperidin-1-yl)-ethanone::MLS001221414::SMR000599968::cid_5938646

SMILES CC(Cc3nc1c(c(C#N)nn1C(C)c2ccc(C(F)(F)F)nc2)c(=O)[nH]3)c4ncccn4

InChI Key InChIKey=RTLQWJIUROGJRD-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 114810   

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 114810BDBM114810(4-oxo-6-(2- (pyrimidin-2- yl)propyl)-1-(1- (6- (tr...)
Affinity DataKi:  1.17nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent