BDBM11552 (3R)-2-[(4-chloro-1,1-biphenyl-4-yl)methyl]-N-hydroxy-1,2-thiazinane-3-carboxamide 1,1-dioxide::(3R)-2-{[4-(4-chlorophenyl)phenyl]methyl}-N-hydroxy-1,1-dioxo-1,2-thiazinane-3-carboxamide::Sultam Hydroxamate 23b

SMILES ONC(=O)[C@H]1CCCS(=O)(=O)N1Cc1ccc(cc1)-c1ccc(Cl)cc1

InChI Key InChIKey=XBJDUGZISLIDRA-QGZVFWFLSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 11552   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM11552((3R)-2-[(4-chloro-1,1-biphenyl-4-yl)methyl]-N-hydr...)
Affinity DataKi: <2.10nMAssay Description:The enzymatic activities of MMPs were determined with recombinant human version catalytic domains and a fluorogenic peptide substrate. Fluorescence m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM11552((3R)-2-[(4-chloro-1,1-biphenyl-4-yl)methyl]-N-hydr...)
Affinity DataKi: <3.30nMAssay Description:The enzymatic activities of MMPs were determined with recombinant human version catalytic domains and a fluorogenic peptide substrate. Fluorescence m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM11552((3R)-2-[(4-chloro-1,1-biphenyl-4-yl)methyl]-N-hydr...)
Affinity DataKi: <5nMAssay Description:The enzymatic activities of MMPs were determined with recombinant human version catalytic domains and a fluorogenic peptide substrate. Fluorescence m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM11552((3R)-2-[(4-chloro-1,1-biphenyl-4-yl)methyl]-N-hydr...)
Affinity DataKi:  318nM ΔG°:  -8.86kcal/molepH: 7.5 T: 2°CAssay Description:The enzymatic activities of MMPs were determined with recombinant human version catalytic domains and a fluorogenic peptide substrate. Fluorescence m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed