BDBM11570 1b-meta-OMe::5-(aminomethyl)-6-(3-methoxyphenyl)-2-phenylpyrimidin-4-amine::Aminomethylpyrimidine 1bh

SMILES COc1cccc(c1)-c1nc(nc(N)c1CN)-c1ccccc1

InChI Key InChIKey=SKVPIYLYAOJOHK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 11570   

TargetDipeptidyl peptidase 4(Human)
Hoffmann-La Roche

LigandPNGBDBM11570(1b-meta-OMe | 5-(aminomethyl)-6-(3-methoxyphenyl)-...)
Affinity DataIC50: 8.00E+4nMpH: 7.5 T: 2°CAssay Description:DPP-IV inhibitors were measured for their ability to inhibit DPP-IV mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2006
Entry Details Article
PubMed