BDBM11578 5-(aminomethyl)-6-(2,4-dichlorophenyl)-2-phenylpyrimidin-4-amine::Aminomethylpyrimidine 1c::CHEMBL36020

SMILES NCc1c(N)nc(nc1-c1ccc(Cl)cc1Cl)-c1ccccc1

InChI Key InChIKey=CTFXGZSHNLIYDI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 11578   

TargetDipeptidyl peptidase 4(Human)
Graduate University of The Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM11578(5-(aminomethyl)-6-(2,4-dichlorophenyl)-2-phenylpyr...)
Affinity DataIC50: 10nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Graduate University of The Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM11578(5-(aminomethyl)-6-(2,4-dichlorophenyl)-2-phenylpyr...)
Affinity DataIC50: 10nMAssay Description:DPP-IV inhibitors were measured for their ability to inhibit DPP-IV mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2006
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM11578(5-(aminomethyl)-6-(2,4-dichlorophenyl)-2-phenylpyr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human liver microsome cytochrome P450 3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed