BDBM11591 1c-para-CF3::5-(aminomethyl)-6-(2,4-dichlorophenyl)-2-[4-(trifluoromethyl)phenyl]pyrimidin-4-amine::Aminomethylpyrimidine 1cm

SMILES NCc1c(N)nc(nc1-c1ccc(Cl)cc1Cl)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=HQTMVECTONHOFD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 11591   

TargetDipeptidyl peptidase 4(Human)
Hoffmann-La Roche

LigandPNGBDBM11591(1c-para-CF3 | 5-(aminomethyl)-6-(2,4-dichloropheny...)
Affinity DataIC50: 180nMAssay Description:DPP-IV inhibitors were measured for their ability to inhibit DPP-IV mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2006
Entry Details Article
PubMed