BDBM116201 US8637502, 24

SMILES NC(=O)Cn1c2ccccc2n(C2CCN(CC2)C2Cc3cccc4cccc2c34)c(=O)c1=O

InChI Key InChIKey=YCKODQWAIKYAQB-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 116201   

TargetNociceptin receptor(Human)
Purde Pharma

US Patent
LigandPNGBDBM116201(US8637502, 24)
Affinity DataKi:  453nM ΔG°:  -8.04kcal/molepH: 7.4 T: 2°CAssay Description:ORL-1 Receptor Binding Assay Procedures: Membranes from recombinant HEK-293 cells expressing the human opioid receptor-like receptor (ORL-1) (Recepto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Purde Pharma

US Patent
LigandPNGBDBM116201(US8637502, 24)
Affinity DataKi:  3.30E+3nM ΔG°:  -7.47kcal/molepH: 7.4 T: 2°CAssay Description:μ-Opioid Receptor Binding Assay Procedures: Radioligand dose-displacement binding assays for μ-opioid receptors used 0.2 nM[3H]-diprenorphi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetDelta-type opioid receptor(Human)
Purde Pharma

US Patent
LigandPNGBDBM116201(US8637502, 24)
Affinity DataKi:  5.45E+3nM ΔG°:  -7.18kcal/molepH: 7.4 T: 2°CAssay Description:δ-Receptor Binding Assay Procedures: Radioligand dose-displacement assays used 0.2 nM [3H]-Naltrindole (NEN; 33.0 Ci/mmole) with 10-20 μg m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetKappa-type opioid receptor(Human)
Purde Pharma

US Patent
LigandPNGBDBM116201(US8637502, 24)
Affinity DataKi:  6.95E+3nM ΔG°:  -6.54kcal/molepH: 7.4 T: 2°CAssay Description:κ-Opioid Receptor Binding Assay Procedures: Membranes from recombinant HEK-293 cells expressing the human kappa opioid receptor (kappa) (cloned ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent