BDBM116213 US8637502, 47

SMILES O=c1[nH]c2ccc(cc2n(C2CCN(CC2)C2CCCCCCC2)c1=O)N1CCOCC1

InChI Key InChIKey=DUYDGIOXNYEFHX-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 116213   

TargetKappa-type opioid receptor(Human)
Purde Pharma

US Patent
LigandPNGBDBM116213(US8637502, 47)
Affinity DataKi:  559nM ΔG°:  -7.92kcal/molepH: 7.4 T: 2°CAssay Description:κ-Opioid Receptor Binding Assay Procedures: Membranes from recombinant HEK-293 cells expressing the human kappa opioid receptor (kappa) (cloned ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetNociceptin receptor(Human)
Purde Pharma

US Patent
LigandPNGBDBM116213(US8637502, 47)
Affinity DataKi:  584nM ΔG°:  -7.90kcal/molepH: 7.4 T: 2°CAssay Description:ORL-1 Receptor Binding Assay Procedures: Membranes from recombinant HEK-293 cells expressing the human opioid receptor-like receptor (ORL-1) (Recepto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Purde Pharma

US Patent
LigandPNGBDBM116213(US8637502, 47)
Affinity DataKi:  2.82E+4nM ΔG°:  -6.20kcal/molepH: 7.4 T: 2°CAssay Description:μ-Opioid Receptor Binding Assay Procedures: Radioligand dose-displacement binding assays for μ-opioid receptors used 0.2 nM[3H]-diprenorphi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetDelta-type opioid receptor(Human)
Purde Pharma

US Patent
LigandPNGBDBM116213(US8637502, 47)
Affinity DataKi:  5.21E+4nM ΔG°:  -5.84kcal/molepH: 7.4 T: 2°CAssay Description:δ-Receptor Binding Assay Procedures: Radioligand dose-displacement assays used 0.2 nM [3H]-Naltrindole (NEN; 33.0 Ci/mmole) with 10-20 μg m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent