BDBM116221 US8637502, 61

SMILES O=c1[nH]c2ccccc2n([C@@H]2C[C@H]3C=C[C@@H](C2)N3C2CCCCC\C=C/2)c1=O

InChI Key InChIKey=IQQOBQHEIOGKDI-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 116221   

TargetNociceptin receptor(Human)
Purde Pharma

US Patent
LigandPNGBDBM116221(US8637502, 61)
Affinity DataKi:  56nM ΔG°:  -9.19kcal/molepH: 7.4 T: 2°CAssay Description:ORL-1 Receptor Binding Assay Procedures: Membranes from recombinant HEK-293 cells expressing the human opioid receptor-like receptor (ORL-1) (Recepto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetKappa-type opioid receptor(Human)
Purde Pharma

US Patent
LigandPNGBDBM116221(US8637502, 61)
Affinity DataKi:  682nM ΔG°:  -7.81kcal/molepH: 7.4 T: 2°CAssay Description:κ-Opioid Receptor Binding Assay Procedures: Membranes from recombinant HEK-293 cells expressing the human kappa opioid receptor (kappa) (cloned ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Purde Pharma

US Patent
LigandPNGBDBM116221(US8637502, 61)
Affinity DataKi:  1.58E+4nM ΔG°:  -6.55kcal/molepH: 7.4 T: 2°CAssay Description:μ-Opioid Receptor Binding Assay Procedures: Radioligand dose-displacement binding assays for μ-opioid receptors used 0.2 nM[3H]-diprenorphi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetDelta-type opioid receptor(Human)
Purde Pharma

US Patent
LigandPNGBDBM116221(US8637502, 61)
Affinity DataKi:  2.28E+4nM ΔG°:  -6.33kcal/molepH: 7.4 T: 2°CAssay Description:δ-Receptor Binding Assay Procedures: Radioligand dose-displacement assays used 0.2 nM [3H]-Naltrindole (NEN; 33.0 Ci/mmole) with 10-20 μg m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent