BDBM116706 US8637532, 414

SMILES COc1cc(C(=O)NC2=CCCC(C(C)Nc3ncnc4c(C(N)=O)cccc34)=C2)ccn1

InChI Key InChIKey=GRBADRHZGYZJTH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 116706   

TargetAurora kinase A(Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 116706BDBM116706(US8637532, 414)
Affinity DataIC50: 0.530nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetAurora kinase B(Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 116706BDBM116706(US8637532, 414)
Affinity DataIC50: 2.30nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 116706BDBM116706(US8637532, 414)
Affinity DataIC50: 32nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent