BDBM116772 US8637532, 489

SMILES CN(C[C@@H](Nc1ncnc2c1=CCCC=2C(N)=O)c1ccccc1)C1CC1

InChI Key InChIKey=MUFCACSRTIFNRI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 116772   

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 116772BDBM116772(US8637532, 489)
Affinity DataIC50: 66nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetAurora kinase A(Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 116772BDBM116772(US8637532, 489)
Affinity DataIC50: 150nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 116772BDBM116772(US8637532, 489)
Affinity DataIC50: 7.40E+4nMpH: 7.5 T: 2°CAssay Description:The kinase assay is performed as 384-well Flashplate assay (PerkinElmer LAS Germany GmbH). 3.4 nM His6-PDK1(Delta 1-50) (PDK1 that has a His-tag cons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent