BDBM116886 US8637532, 612

SMILES CCN(CC)CCNCc1cc(C(N)=O)c2ncnc(NCc3cccc(NC(O)c4ccc(OC)cc4)c3)c2c1

InChI Key InChIKey=JLOVLGWBSKSKJB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 116886   

TargetAurora kinase A(Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 116886BDBM116886(US8637532, 612)
Affinity DataIC50: 7nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 116886BDBM116886(US8637532, 612)
Affinity DataIC50: 5.00E+3nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent