BDBM116916 US8637532, 643

SMILES C[C@@H](Nc1ncnc2c(cccc12)C(N)=O)c1ccc(F)c(NC(=O)c2ccc(OC(F)(F)F)cc2)c1

InChI Key InChIKey=YCYPFPIRBBLPCG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 116916   

TargetAurora kinase A(Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 116916BDBM116916(US8637532, 643)
Affinity DataIC50: 0.440nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent